. Earth Science News .
EPIDEMICS
China tests entire city for virus as WHO slams herd immunity idea
By Beiyi Seow, with AFP Bureaus
Beijing (AFP) Oct 13, 2020

Hong Kong scientists say anti-microbe drug successful against coronavirus
Hong Kong (AFP) Oct 12, 2020 - An affordable anti-microbial drug used to treat stomach ulcers and bacterial infections has shown promise in combatting the coronavirus in animals, scientists in Hong Kong announced Monday.

Researchers set out to explore whether metallodrugs -- compounds containing metal that are more commonly used against bacteria -- might also have anti-viral properties that could fight the SARS-CoV-2 coronavirus.

Using Syrian hamsters as tests subjects, they found that one of the drugs, ranitidine bismuth citrate (RBC), was "a potent anti-SARS-CoV-2 agent".

"RBC is able to lower the viral load in the lung of the infected hamster by tenfold," Hong Kong University researcher Runming Wang told reporters on Monday as the team presented their study.

"Our findings demonstrate that RBC is a potential anti-viral agent for Covid-19."

The coronavirus has killed more than a million people since it first emerged in China last December and then spread across the globe.

As scientists scramble to find a vaccine, they have also been scouring readily available drugs that might alleviate symptoms caused by the Covid-19 disease or help the body fight infection.

Remdesivir, a broad-spectrum antiviral drug, and dexamethasone, a type of corticosteroid, have both been identified as having some success against the virus. Both were used by doctors to treat US President Donald Trump after he contracted Covid-19.

But they have drawbacks.

Remdesivir is expensive and there is a global shortage while dexamethasone has immunosuppression effects that are risky for all but the most ill patients. Other drug cocktails have shown liver damage can be a risk.

The Hong Kong scientists said RBC was a commonly available drug used against stomach ulcers with a safe and comprehensive pharmacological profile.

"It's been used for decades so it's pretty safe," Wang said.

They added that their research, which has been published in the journal Nature Microbiology, suggested other metallodrugs might also have success against the virus and should be further explored.

China rushed Tuesday to test an entire city of nine million within days after a minor coronavirus outbreak, as the WHO warned that letting the pathogen run free to achieve herd immunity was "scientifically and ethically problematic".

The virus is still spreading rapidly around the world, with well over 37 million infections, and nations that had suppressed their first outbreaks are now struggling with fresh surges -- especially in some parts of Europe.

In the absence of a vaccine, governments are wary of allowing the virus to spread unchecked, with China launching a sweeping drive to test all residents of Qingdao after a handful of cases were detected on Sunday.

"As of 8 am... our city has taken 3.08 million samples for nucleic testing," the city's health commission said Tuesday, adding that no new positive samples were found.

Chinese officials intend to test the entire city -- around 9.4 million people -- by Thursday.

In scenes contrasting with the fumbled testing efforts of other nations, health workers in protective clothing swiftly set up tents and residents queued deep into Monday night to provide samples.

In opposition to economically painful lockdowns and social distancing, there have been proposals in some countries to let the coronavirus circulate in the population to build up "herd immunity" -- where so much of the population has been infected there are insufficient new victims for the virus to jump to.

But the World Health Organization said such plans were unworkable, and required mass vaccinations to work.

"Herd immunity is achieved by protecting people from a virus, not by exposing them to it," WHO chief Tedros Adhanom Ghebreyesus said Monday, describing the idea as "scientifically and ethically problematic".

"Allowing a dangerous virus that we don't fully understand to run free is simply unethical. It's not an option."

Further illustrating the challenge, a study published in The Lancet Infectious Diseases journal indicated that exposure to the virus may not guarantee future immunity -- and the second infection could come with even more severe symptoms.

- Vaccine setback -

The pandemic has claimed more than one million lives worldwide, and spurred breakneck efforts to develop vaccines and effective treatments.

Some have made it to late-stage clinical testing, but the optimism was dented Monday when Johnson & Johnson announced it had temporarily halted its 60,000-patient trial because of an unexplained illness in one participant.

There are ten firms conducting Phase 3 trials of their candidates globally, including Johnson & Johnson.

The pharma giant has been awarded about $1.45 billion in US funding under Operation Warp Speed, championed by President Donald Trump, who is keen for a political boost ahead of the November election with a coronavirus breakthrough.

Critics have excoriated Trump for his handling of the crisis, with more known infections and deaths in the United States than anywhere else in the world.

Trump was sidelined from the campaign trail for 10 days after he got Covid-19, but returned to the stage Monday.

"I went through it and now they say I'm immune... I feel so powerful," Trump told a cheering crowd in Florida, few of whom wore masks.

His claim of immunity is unproven.

- 'Catastrophic, catastrophic' -

European nations are trying to contain new surges in infections, and governments are rolling out tighter restrictions to avoid the devastation of the earlier outbreaks.

Cases have soared in France, Germany, Poland, and the Czech Republic in recent days.

And there has also been a spike in Britain, which has the highest death toll in Europe.

Prime Minister Boris Johnson ordered pubs in Liverpool to shut as part of a new strategy to tackle a surge in infections.

He said businesses forced to close would get support from the government, but his focus on shutting hospitality venues sparked anger.

"Catastrophic, catastrophic," said Simon Ashdown, owner of the Chepstow Castle pub in Liverpool.

"I don't think there'll be many businesses after this lockdown."

bur-qan/hg

JOHNSON & JOHNSON


Related Links
Epidemics on Earth - Bird Flu, HIV/AIDS, Ebola


Thanks for being here;
We need your help. The SpaceDaily news network continues to grow but revenues have never been harder to maintain.

With the rise of Ad Blockers, and Facebook - our traditional revenue sources via quality network advertising continues to decline. And unlike so many other news sites, we don't have a paywall - with those annoying usernames and passwords.

Our news coverage takes time and effort to publish 365 days a year.

If you find our news sites informative and useful then please consider becoming a regular supporter or for now make a one off contribution.
SpaceDaily Contributor
$5 Billed Once


credit card or paypal
SpaceDaily Monthly Supporter
$5 Billed Monthly


paypal only


EPIDEMICS
Scientists warn of human-to-wildlife COVID-19 transmission risk
Washington DC (UPI) Oct 09, 2020
The risk of human-to-wildlife COVID-19 transmission is real and significant, scientists warn in a paper published this week in the journal Mammal Review. Although the exact origins of the COVID-19 pandemic aren't clear, most researchers estimate the virus made the jump from bats to pangolins before infecting humans. Now, scientists worry the virus could make the jump from humans back into wild animal populations. If COVID-19 managed to infect and spread among wild animals, it could pose ... read more

Comment using your Disqus, Facebook, Google or Twitter login.



Share this article via these popular social media networks
del.icio.usdel.icio.us DiggDigg RedditReddit GoogleGoogle

EPIDEMICS
Yemen rebels slam WFP after Nobel Peace Prize win

WFP frontline staff express shock, pride over Nobel

Peace and ending hunger 'go hand in hand', WFP says after Nobel win

Maryland Company Licenses NASA's New Search and Rescue Technology

EPIDEMICS
IBM reorganizes to focus on cloud computing

Mobile games thrive, even as pandemic keeps players home

Geologists solve puzzle that could predict valuable rare earth element deposits

Greece, Microsoft announce 1-bn-euro cloud investment

EPIDEMICS
Underwater robots to autonomously dock mid-mission to recharge and transfer data

Global lake warming trend threatens freshwater species

France's Engie sells crucial stake in Suez

Tuna value dropping, industry must plan ahead: report

EPIDEMICS
Arctic odyssey ends, bringing home tales of alarming ice loss

Meltwater lakes are accelerating glacier ice loss

Antarctic Peninsula at warmest in decades: study

Discharges from western North America disrupted climate during last ice age

EPIDEMICS
World Food Programme wins Nobel Peace Prize

Unique vine 'greenhouses' found by 91-year-old nature volunteer

Study: Sicker livestock emit more methane, accelerating climate change

French MPs vote to freeze ban on bee-killing pesticides

EPIDEMICS
Locals flee as strengthening hurricane barrels toward southern US

Rain floods Greece's largest migrant camp

Double trouble: Louisiana pounded by two hurricanes in six weeks

Weary Louisiana residents assess damage from latest hurricane

EPIDEMICS
3 Mali national guardsmen killed in overnight attack

After Sudan's peace deal, the hard task begins of gathering the guns

USS Hershel 'Woody' Williams conducts exercises with Nigerian navy

U.S., Morocco renew military ties to 2030

EPIDEMICS
Musical training boosts attention, working memory in children

Past tropical forest changes drove megafauna and hominin extinctions

Study finds preserved brain material in Vesuvius victim

Neuroscientists discover a molecular mechanism that allows memories to form









The content herein, unless otherwise known to be public domain, are Copyright 1995-2024 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. General Data Protection Regulation (GDPR) Statement Our advertisers use various cookies and the like to deliver the best ad banner available at one time. All network advertising suppliers have GDPR policies (Legitimate Interest) that conform with EU regulations for data collection. By using our websites you consent to cookie based advertising. If you do not agree with this then you must stop using the websites from May 25, 2018. Privacy Statement. Additional information can be found here at About Us.